
Pet-friendly holiday rentals in Mesa County
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Mesa County
Guests agree: these pet-friendly homes are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Mesa County pet-friendly home rentals
Pet-friendly house rentals

2 Bedroom Ranch House
Homely and secluded slice of farm house tucked away in a beautiful part of CO. Any easy way to switch off the routine and life pace and bring your right into the present moment!

Cozy 2-Bedroom House on a quiet Residential Street
Great place to stay! Has everything you need and good location. Thanks!

70 Year old Ranch house on the Ranch
Thank you so much for your patience and flexibility with us during our stay. The place was perfect and we so appreciate it. Thanks again

Fully Stocked 3 BR HOME - Work & Play w/fast WiFi
Great location, super comfy home and awesome attentive hosts! Can’t wait to come back!

The Hill House - Walk to CMU, stadium & downtown
The house was great and a short walk to a playground. There were lots of extra blankets, pillows and linens which was perfect for the kids sleeping on the futon. Neighborhood felt safe and the house is on a quiet street.

The Centennial House ~ Historic 6BR, 3BA home.
The Centennial House was perfect for our extended family to gather. The giant dining room table and spacious kitchen were perfect for meals and board games. Everyone had a comfortable room to stay in and our Sheltie had so much fun racing the kids around the house. Location is close to Colorado National Monument and the grand Junction area while also being out away from the freeway and busy traffic areas.

Walkable Downtown Historic Home: A/C, Patios, BBQ
Great location! Walking distance to downtown and not far to hiking/skiing. Would definitely stay again, Amri was very responsive.

Paonia Victorian Farmhouse
We had a relaxing stay at this lovingly restored Victorian Airbnb. Classical music and soft lighting awaited us upon entering this cozy home. My husband said that the bed was one of the most comfortable he ever slept in. There was a family of deer that frolicked in the yard in the morning and at dusk. The views from the back yard were spectacular! We appreciated the extremely well stocked kitchen and numerous cozy spaces that were created throughout this historic home.
Pet-friendly home rentals with a pool

Escalante Tent at Gateway Glamping
This was our second stay in the Escalante tent. Our first stay was in 2022. The property was already awesome back then, but the hosts have done a TON of work these past 2 years from the community pool area, bathrooms and pathways, to all the decorations, lighting, and sitting areas that give an overall inviting feeling to the property. We've stayed at other glamping properties, but this one is by far the best. The scenery is top notch. There are no crowds in Gateway, so it is very peaceful. The drives south towards Naturita along the Dolores and over the pass to Moab are incredible. The tent comes with everything you need to cook/eat, build a fire, or just relax. Also, the bed is one of the most comfortable I've slept on, even compared to expensive hotels I've stayed in. On top of it all, the Escalante is pet friendly. Our dog loved this place. He's since passed on to bigger and better things, but we'll make the Escalante tent a regular stop to celebrate his memory.

Peach Pad! hot or cool tub 2 bedrooms 2 bathrooms
It was a perfect get away and close to home. The hot tub was our favorite part, and my kids had a blast in it with us. The views were incredible in the evening we got to watch the sunset as we were in the hot tub. The beddibg was very clean and great smell, it felt like at home! Plenty of towels and wrobes perfect for after the hot tub! Will be back soon!!! 10/10

Bookcliff Ranch Casita (Little House)
So beautiful and quiet. The perfect place to enjoy quiet, beautiful vistas and privacy while be close to Fruita and Grand Junction. View of the Monument and Book Cliffs especially at sunrise was breath taking. There were a million stars at night and it really was relaxing to be away from it all. Would highly recommend!

The Beatrice Estate
We had a wonderful stay at this beautiful home. Tons of indoor and outdoor space, very clean, extremely kid (and pet) friendly and a beyond responsive host. We would absolutely consider going back and appreciated the thoughtfulness of our host/caretaker thru all their little welcome gestures, flexible accommodations and helpfulness in getting us settled at home along with familiarizing us with Grand Junction.

Cozy lake house, great location
Clean and great location

Fruita farm adventure
Wow wow and wow. I wish I could’ve stayed more time at Cindy’s farm. I was lucky enough to find this place to rest along the way on my cross country roadtrip but ended up finding one of my favorite views here. The sunrise views you wake up alone would make me want to come back in the future. Thank you Cindy for sharing your home ◡̈

The Honey Bee @ Palisade Legends
This was our second time here because we liked it so much. It was very cozy and a great spot when you have dogs.

Adventure Home Base - 7 Blocks to Downtown!
Cute little house with a great back yard for hanging out in the evening. Centrally located in town near all the events and locations.
Private, pet-friendly home rentals

Paonia Tiny Home Reprieve, Pet Friendly!
Felt right at home and really enjoyed our stay. Could definitely fall in love with the town. I will recommend to all of my friends!

Fanciful Fruita Farm!
Very charming and spacious listing! Hosts were friendly and helpful. We would stay again.

Galloway Ranch Palisade Colorado
What a beautiful oasis in the Palaside countryside. The house was charming and well maintained. The large fenced area outside was greatly appreciated by the dog. The setting itself is peaceful and offers great views of the mountains. It is also a great jumping off point to see the many things the area has to offer. Would love to stay again, for longer next time!

Getaway in Paradise
Incredible hosts. You know the phrase “give more than you take” — that’s how Amanda and her husband treated me, with warmth and hospitality after a long arduous journey on the road. It was very appreciated. Fire and star gazing were wonderful as well. Thank you so much!

Chic Indigo Digs : 3 BR,Cool Kitchen, Zen Patio!
We loved this cute townhouse in Grand Junction! The location was perfect, and the home was well appointed. The kitchen was very efficient with everything you needed! The bathrooms were super clean with double vanities. The beds were comfortable with luxurious bedding. There is plenty of parking on the street right outside the rental. The layout was great for our group with the private suite on the third floor and two bedrooms with a shared bath on the second. We would stay there again in a heartbeat!

Come, relax on the farm @ Tres Chivos Farmhouse!
Hosts were available and friendly. Loved how close the horses were (open blinds and see them)!

Perfectly peaceful in the Preserve
We LOVED our stay here. The property is amazing. It’s so fun to explore the wilderness that surrounds it. We loved sitting by the pond and watching the frogs. We also really enjoyed the fun outdoor games available. Our dogs had so much room to run and absolutely loved it. The inside of the home is beautiful. Rachel has really thought of everything to make your stay enjoyable. We also loved how close the property was to all of our activities. We went horseback riding, rafting, wine tasting and visited the Colorado National Monument…all within 10 minutes of the property. Highly recommend!!

Lakefront animal sanctuary house & guest house
There's no word to describe how amazing this place is! if you are an animal lover, you have to stay here! it was a little slice of heaven and we really enjoyed spending our christmas at this place. We went out every morning and fed the animals treats, got to interact with them as much as we wanted. It was really cool to wake up, open my eyes and see all the animals out the window. awe are big dog lovers in our family and were missing our own pets so it was really great to have the dogs wandering around the property, and we could let them in the house with us to hang out any time we wanted. We will definitely be back to this place!
Destinations to explore
- Smoking-friendly rentals Mesa County
- Family-friendly rentals Mesa County
- Rentals with outdoor seating Mesa County
- Tiny house rentals Mesa County
- Rentals with pools Mesa County
- Apartment rentals Mesa County
- Rentals with a patio Mesa County
- Farm stay rentals Mesa County
- Rentals with a washing machine and dryer Mesa County
- Rentals with an EV charger Mesa County
- Bed and breakfasts Mesa County
- Rentals with a kayak Mesa County
- Rentals with a hot tub Mesa County
- Rentals with a firepit Mesa County
- House rentals Mesa County
- Rentals with lake access Mesa County
- Cabin rentals Mesa County
- Rentals with a fireplace Mesa County
- Private suite rentals Mesa County
- Flat rentals Mesa County
- Family-friendly rentals Mesa County
- Pet-friendly rentals Colorado
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom