Mansion holiday rentals in Panama
Find and book unique mansions on Airbnb
Top-rated mansion rentals in Panama
Guests agree: these mansions are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama mansion rentals
Luxury mansion rentals
Villa in Panamá
5.0 out of 5 average rating, 32 reviewsBreathtaking Views Mansion w/King Beds
Home in Río Hato
4.95 out of 5 average rating, 75 reviewsSpectacular beachfront house in Buenaventura!
Villa in Buenaventura, El Chirú
4.84 out of 5 average rating, 45 reviewsLake House | Pool | King Beds | Next to Beach Club
Home in Panamá
5.0 out of 5 average rating, 9 reviewsUnique 4 room house - direct access to the beach
Villa in Playa Venao
4.98 out of 5 average rating, 61 reviewsCasa Aqua: Amazing beach front house - Playa Venao
Flat in Maria Chiquita
4.97 out of 5 average rating, 62 reviewsSpacious 4Br Beachside Getaway at Playa Escondida
Flat in Maria Chiquita
4.95 out of 5 average rating, 21 reviewsPenthouse in Playa Escondida 4 bedrooms
Villa in Bejuco
4.96 out of 5 average rating, 78 reviewsBeach house in Punta Chame, Villa frente al mar
Pet-friendly mansion rentals
Home in San Carlos
4.93 out of 5 average rating, 88 reviewsBeach House-Ocean View Rooftop Jacuzzi & Pool
Villa in Portobelo
5.0 out of 5 average rating, 43 reviewsEntire Villa with pool in front of beach!
Home in Río Hato
4.98 out of 5 average rating, 97 reviewsRenewed / Make yourself at Home / Enjoy
Home in Playa Bluff
5.0 out of 5 average rating, 17 reviewsJungle House 100m from the beach
Flat in San Carlos District
4.99 out of 5 average rating, 81 reviewsAmazing Oceanfront apartment in San Carlos
Villa in Bocas del Toro
5.0 out of 5 average rating, 56 reviewsCasa del Mar - eco aqua villa
Apartment in San Carlos District
4.97 out of 5 average rating, 38 reviewsPunta Caelo Beach Front View
Home in Gamboa
4.86 out of 5 average rating, 88 reviewsBirdHouse@ Gamboa Panamá Canal
Mansion rentals with a pool
Apartment in Maria Chiquita
5.0 out of 5 average rating, 22 reviewsPlaya Escondida Lux Beachfront Haven:Oceanview Apt
Flat in Panamá
5.0 out of 5 average rating, 21 reviewsTop Floor Condo 6 bedroom with amazing views
Flat in Río Hato
5.0 out of 5 average rating, 18 reviews4 Bedroom Private Pool Paradise in Buenaventura
Flat in Panama City
4.95 out of 5 average rating, 19 reviews22M Spectacular Penthouse New Design Oceanview
Home in Pedasí
4.83 out of 5 average rating, 6 reviewsOcean View From The Jungle!
Flat in El Chirú
4.94 out of 5 average rating, 85 reviewsBuenaventura Golf & Beach Resort Lux Apartment
Villa in Las Escobas del Venado
4.95 out of 5 average rating, 21 reviewsBreathtaking Ocean Villa. Casa de Vida
Home in Bastimentos
4.8 out of 5 average rating, 99 reviewsSpacious, Over the Water Home with Plunge Pool
Destinations to explore
- Rentals with a fireplace Panama
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- Family-friendly rentals Panama
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- Wheelchair-accessible rentals Panama
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- Villa rentals Panama
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