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Guest house holiday rentals in South Carolina

Find and book unique guest house rentals on Airbnb

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Popular amenities for guest house rentals in South Carolina

Family-friendly guest house rentals

Guest favourite
Guest house in Pawleys Island
4.95 out of 5 average rating, 246 reviews

Studio Apt - (Pets/beach/pool/golf)

MetinRating, 5 stars3 months ago
TJ was a very helpful, responsive, and friendly. The space was very enjoyable, great location
Top guest favourite
Guest house in Mount Pleasant
4.97 out of 5 average rating, 244 reviews

Bungalow Under The Oaks

SandrineRating, 5 stars1 day ago
We stayed here for a long weekend and will 100% be back! Along with a very clean house, Jessica had everything needed in the kitchen along with extra bathroom products in case we forgot anything. Even had necessities if you brought your pet! Location was very close to everything and felt very private and a cute getaway for 2.
Top guest favourite
Guest house in Summerville
4.88 out of 5 average rating, 796 reviews

New Loft in Historic Summerville

AmyRating, 5 stars1 day ago
We loved our stay at Jacquelynn's! We had to travel with our two older, yet anxious, dogs for a wedding and it turned out to be the perfect place for us. The loft is detached from the home, making it much more private to go to and from. The place was spotless with cute decor. Even though it is a smaller space, she has everything you need to make your stay comfortable. Lots of towels and blankets as well as silverware, coffee pot, and mugs. I was pleasantly surprised at how the bathroom was actually quite spacious for the small space. The most important and best part for us was the peace and quiet. We typically have to worry about outside noise as our dogs will bark at any and every noise they hear. But the loft is nestled in such a quiet and quaint neighborhood, making it perfect for anyone with anxiety ridden dogs. I highly recommend Jacquelynn's loft!
Guest favourite
Guest house in North Charleston
4.93 out of 5 average rating, 394 reviews

Cozy Park Circle, Charleston Guest House

CaitlynRating, 5 stars1 month ago
Very convenient place to Park Circle and the major highways in Charleston.
Top guest favourite
Guest house in Donalds
4.99 out of 5 average rating, 371 reviews

Home on the farm

JamesRating, 5 stars1 day ago
Awesome little getaway. From fishing to riding the trails on the property l and splashing around in the pool. It was peaceful. Kids had an awesome time.
Superhost
Guest house in Charleston
4.84 out of 5 average rating, 117 reviews

Romantic Beach Style Cottage close to everything!

NatalieRating, 5 starstoday
Clean & conscious hosts! Mindful of needs that may crop up, lovely home & family. Flexible! Perfect oasis away from the bustle of Charleston.
Guest favourite
Guest house in Salem
4.89 out of 5 average rating, 307 reviews

Mountain Edge Loft

JewelRating, 5 stars3 months ago
Beautiful land and home, cute dogs and chickens, the bread was delicious and i definitely recommend California's Mexican Grill, it was yummy!! The fire pit was so warm. Everything was clean and comfortable, Marsha responded to our messages in a short time and was very kind, will recommend to friends!
Guest favourite
Guest house in Greenville
4.92 out of 5 average rating, 662 reviews

Historic 19th Century Cabin/Guest House

MelisaRating, 5 stars1 week ago
Tony was welcoming and accommodating. One reviewer mentioned traffic noise, and while the cabin does sit next to a busy thoroughfare, I didn’t find the noise too disturbing. Overall, worth the price for the convenient location, private parking, and full kitchen. Bonus: Very close to the Swamp Rabbit Trail—we were dropped off at the Ingle’s grocery on Geer Highway and rode to the cabin to from the trail. Approximately 22 miles.

Guest house rentals with a patio

Guest favourite
Guest house in Charleston
4.94 out of 5 average rating, 236 reviews

Quaint Cottage Studio in Ashley Forest (Avondale), New Zealand

JenniferRating, 5 stars1 week ago
John and his family offer a cozy place to rest after exploring the nearby neighborhoods by foot and the region by car. A comfy bed, a responsive host, a central location and great local recommendations were highlights.
Top guest favourite
Guest house in Campobello
4.97 out of 5 average rating, 115 reviews

Bungalow on a 3 acre mini farm

BrandiRating, 5 stars2 weeks ago
Wow—what a gem of a stay! Jonathan is one of the kindest and most thoughtful hosts we’ve ever had. We loved the fresh eggs and getting to hear how he got into hosting—it really added a personal and meaningful touch to our visit. The place itself felt like a page straight out of a storybook—cozy, charming, and full of little details that made it feel magical. There was so much to do, from fun games to quiet spots to relax. The tub was incredibly relaxing—exactly what we needed after a long day of hiking. Total bliss! We’re already planning to try out the fire pit next time too. And don’t worry about going hungry—Jonathan provides so much food. You definitely won’t starve here! Thank you again, Jonathan, for such a wonderful and memorable stay. Can’t wait to come back!
Guest favourite
Guest house in Batesburg-Leesville
5 out of 5 average rating, 8 reviews

Beautiful Lake Front 1 bedroom Guest House

TracyRating, 5 stars6 months ago
Rhonda was always willing to help with anything I needed. During Hurricane Helen we lost power and water. Rhonda traveled to North Carolina and picked up a generator to take care of us. Rhonda is willing to go the extra mile to ensure her guests have a great stay in her guests house. I will definitely stay there again.
Superhost
Guest house in Myrtle Beach
5 out of 5 average rating, 10 reviews

Cozy 1 Bdrm Cottage~ 1mi to beach~Sleeps4

CarissaRating, 5 stars4 months ago
Very nice and cozy cottage. The bed was very comfortable! We loved that we could bring our dog and that it was fenced in! They were very accommodating and let us stay a little past check out so we could spend more time with our family.
Top guest favourite
Guest house in Inman
4.99 out of 5 average rating, 119 reviews

Foothills Favorite

MackRating, 5 starstoday
Our stay was great! Check in was super easy and there were super clear instructions for checking in and out. The space itself was spotless and super comfortable. Would stay again!
Top guest favourite
Guest house in Johns Island
4.96 out of 5 average rating, 114 reviews

Driftwood Cottage

YianniRating, 5 stars4 days ago
Terry’s place was perfect! The space was spacious, very clean, comfortable, and extremely thoughtful. Terry is a proper gentleman and was kind and quickly responsive to any questions we had. Kiawah is only a 20 minute drive away, the Angel Oak is minutes away, and some amazing restaurants (Royal Tern and The Wild Olive) are very close by. I got engaged during this trip and so Terry’s place will hold an even sweeter place in my heart.
Guest favourite
Guest house in North Charleston
4.92 out of 5 average rating, 131 reviews

My Happy Place

BridgetRating, 5 starstoday
We loved our stay at the pool house! It had everything we needed and the location was great. I would highly recommend it!
Top guest favourite
Guest house in Greenville
4.97 out of 5 average rating, 129 reviews

Finished Room over Garage (FROG) on Reedy River

JuanitaRating, 5 stars1 week ago
It was so beautiful and peaceful A beautiful view to drink your morning Coffee So quiet no traffic sounds Very very clean Couch and bed very comfortable I really enjoyed the trail great walk I loved everything Bret was a great host Always quick to answer questions Checked to see if we needed anything So friendly I would stay again It was such a great stay😄😄😄😄😄😊

Guest house rentals with a washing machine and dryer

Guest favourite
Guest house in Charleston
4.85 out of 5 average rating, 121 reviews

CHS Guest house w/ Pool & Hot Tub on Golf Course

KarenRating, 5 stars3 weeks ago
The home was neat & clean, conveniently located, private, and quiet. We had so much fun visiting many parts of Charleston with the guest house as our homebase. The home had everything our small family needed for our stay and more! Alicia was a gracious, respectful, and responsive host. She even brought extra supplies to us in case we needed them! We would welcome the opportunity to be a guest with her again.
Top guest favourite
Guest house in Mount Pleasant
4.99 out of 5 average rating, 146 reviews

Groves Carriage House, near Shem Creek

JimiRating, 5 stars1 week ago
Wonderful, responsive hosts. This above garage unit has everything you need. The neighborhood is very accessible to anywhere you want to go. 5 minutes from Shem Creek. 15 minutes to Sullivan’s Island or Isles of Palms. Roughly 10-15 minutes from Downtown Charleston. The hosts were very helpful with any of my simple needs. I would definitely stay here again.
Top guest favourite
Guest house in Beaufort
4.98 out of 5 average rating, 407 reviews

The Wren Guest House

BerkleyRating, 5 stars6 days ago
Absolutely charming! Would definitely come back and recommend to others! Had everything we needed! Beaufort is a hidden gem and The Wren was perfect! Thank you! 😍 Berkley and Martha Gray
Top guest favourite
Guest house in Bluffton
4.96 out of 5 average rating, 358 reviews

Old Town Bluffton Carriage Apt.

WilliamRating, 5 stars3 weeks ago
Was a great experience, a beautiful place with every amenity. Really appreciated the attention to detail, had everything you could want in a vacation type rental. Well thought out place, plenty of info available in binders and posts. Not a big traveller but you're sure on top of my list for a return visit to the area. Thanks!
Top guest favourite
Guest house in Westminster
4.99 out of 5 average rating, 169 reviews

Lit'l Bit O' Heaven- Rocky Top Lodge

SharonRating, 5 stars2 weeks ago
Absolutely loved this little cabin. Very comfortable and would definitely stay again.
Top guest favourite
Guest house in Bluffton
4.98 out of 5 average rating, 130 reviews

Carriage House at 12 Lawrence

KathyRating, 5 stars3 weeks ago
We enjoyed our stay at Kristin and Tyler’s bungalow very much! The location was perfect for our nephew’s wedding in Old Town Bluffton, and the bungalow was clean, nicely decorated, and well equipped. We would definitely stay again if in the area, and highly recommend it to others!
Top guest favourite
Guest house in Charleston
4.99 out of 5 average rating, 293 reviews

Spacious Daniel Island Apartment

NelleRating, 5 starstoday
We had a wonderful stay at David’s. The space was exactly what we were looking for - clean, quiet, and comfortable. Daniel Island is beautiful, and downtown Charleston and Mount Pleasant are both very accessible by car/Uber. David was very communicative and a great host - we would love to stay here again!
Guest favourite
Guest house in Charleston
4.96 out of 5 average rating, 168 reviews

Charleston Casita near Folly Beach *Dog Friendly*

KimberlyRating, 5 stars1 week ago
We had a great stay at the Casita. Beautiful interior with modern appliances and very clean and quiet. There was a nice grassy area for our pup to run around and stretch his legs. Host was super responsive. We will be back again. Highly recommend!

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